Why EIS Tax Relief is Transforming UK Biotech Funding
What if you could back a cutting-edge biotech firm and cut your tax bill at the same time? That’s exactly what EIS tax relief makes possible. In recent years, the UK’s Enterprise Investment Scheme has turned early-stage investing into a powerful lever for entrepreneurs and investors alike. Thanks to generous income tax and capital gains exemptions, savvy backers can deploy funds with greater confidence and enjoy a significant cushion on potential losses.
This dynamic environment set the stage for Enhanc3D Genomics to secure a staggering £10 million Series A round. Their GenLink3D™ platform, which decodes the 3D structure of our genome, is a perfect match for forward-thinking investors hunting for innovation plus fiscal perks. And platforms like Oriel IPO, with its commission-free, tax-focused marketplace, make navigating these incentives seamless. Revolutionising Investment Opportunities with EIS tax relief
The GenLink3D Breakthrough and the £10M Series A Milestone
Enhanc3D Genomics burst onto the scene with a novel approach to the genome’s non-coding regions. Most sequencing methods look at DNA like beads on a string. GenLink3D™ maps it in three dimensions. That matters because how genes fold and interact in space largely dictates their function. With this level of insight, researchers can isolate biomarkers for autoimmune diseases, cancer and ageing.
Backed by heavyweights like BGF and Parkwalk Advisors, the biotech’s Series A is a vote of confidence. The fresh capital will accelerate dataset generation, expand the Cambridge team and move into purpose-built facilities at St John’s Innovation Centre. As CEO Debora Lucarelli explains, the investment validates years of development and positions Enhanc3D to partner on diagnostic and therapeutic projects across multiple disease areas.
From Lab to Boardroom
- Funders: BGF, Parkwalk, Bioqube Ventures, private angels
- Technology: High-resolution promoter capture, machine learning integration
- Focus areas: Autoimmune markers, cancer targets, biomarkers for ageing
This is more than just a cash injection. It’s a showcase of how targeted tax incentives can funnel serious funds into high-risk, high-reward science. EIS tax relief itself offers up to 30% income tax relief on investments, plus exemption from capital gains tax if held for three years. That’s a compelling pitch for anyone with a taste for biotech’s frontier.
Understanding EIS Tax Relief: A Deep Dive
What Is EIS Tax Relief?
At its core, the Enterprise Investment Scheme (EIS) provides:
- Up to 30% income tax relief on investments up to £1 million per tax year
- Capital gains tax exemption on disposals after a three-year qualifying period
- Loss relief that can be offset against income or gains
- Deferral of capital gains tax on other assets if you reinvest gains into EIS-eligible companies
Put simply, if you invest £100,000 into a qualifying biotech startup, you immediately cut your income tax bill by £30,000. On top of that, if things go well and you sell after three years, any profit is tax-free.
Why Biotechs Love EIS
Biotech firms often burn cash before reaching revenue. That makes fundraising tough. EIS offers a safe harbour for investors worried about early losses. It cushions downside risk and aligns government priorities with life-changing science. As the UK government ramps up funding for R&D, EIS becomes an even more attractive way to back tomorrow’s medical breakthroughs.
Oriel IPO’s Role in Seamless EIS Investment
Investing via EIS can sound complex. You need to check eligibility, ensure compliance, and navigate paperwork. That’s where Oriel IPO shines.
Commission-Free, Transparent Platform
Unlike traditional equity crowdfunding platforms that skim a percentage off your investment, Oriel IPO operates on a subscription model. No hidden fees. No surprises. When you commit capital, 100% of it goes to the startup—minus your own subscription fee.
Curated, Vetted Opportunities
Oriel IPO doesn’t just list any company. Each firm undergoes due diligence for SEIS/EIS eligibility and growth potential. You get a snapshot of risk and reward up front. Plus, the platform offers guides, webinars and dedicated tools to demystify EIS tax relief. No need to hire an accountant just to read the small print.
Comparing EIS Platforms: Why Oriel IPO Stands Out
Traditional Crowdfunding vs. EIS-Focused Marketplaces
Platforms like Seedrs and Crowdcube paved the way for equity crowdfunding. They gave the public access to startup investing. But they often charge 5% or more in fees. And the sheer volume of pitches can be overwhelming.
EIS-focused marketplaces such as InvestingZone or Crowd for Angels add tax relief to the mix, but they still take commission. Oriel IPO flips the model by combining a flat subscription approach with curated, tax-efficient deals. That blend of clarity, cost-effectiveness and education is a rare find.
Commission Models and Investor Confidence
- Seedrs/Crowdcube: 5–7% fees on funds raised
- InvestingZone: Variable fees + platform charges
- Oriel IPO: Transparent subscription fees, no cut of the investment
The result? Higher net proceeds to founders and clearer cost expectations for investors. That trust is priceless when you’re backing biotech bets with inherent technical risk.
Practical Steps for Investors: Leveraging EIS Tax Relief via Oriel IPO
1. Check Your Eligibility
- Be UK taxpayer, willing to hold shares for three years
- Invest in qualifying early-stage companies
- Keep records for HRMC compliance
2. Sign Up on Oriel IPO
Create an account, pick your subscription tier, and browse vetted biotech opportunities. You’ll see each company’s EIS potential clearly flagged.
3. Commit Funds and Claim Relief
Once your investment goes through, you’ll receive the relevant EIS3 certificates. Use those to claim income tax relief against your self-assessment.
By following these steps, you’re well on your way to boosting your portfolio and cutting your tax bill. Explore how EIS tax relief can work for you
The Future of EIS Investments in UK Biotech
Emerging Trends
- Knowledge-intensive EIS funds targeting deep tech and genomics
- Hybrid public-private partnerships unlocking larger rounds
- Growth in secondary markets for EIS-qualifying shares
Maximising Returns with Innovation
EIS tax relief is not a silver bullet. You still need to do your homework. But by combining the cushion of tax benefits with platforms like Oriel IPO, you gain access to high-potential startups with lower friction. That mix could define the next wave of UK biotech stars.
Conclusion: Embracing EIS Tax Relief for Tomorrow’s Biotech
Enhanc3D Genomics’ £10 million Series A is proof that deep science and smart tax policy can join forces. For investors and founders, the message is clear: EIS tax relief isn’t just an incentive. It’s a catalyst. And platforms like Oriel IPO are making it easier every day to back breakthrough innovation without breaking the bank.
Whether you’re an experienced angel or a first-time backer, the time to explore EIS opportunities is now. Discover the power of EIS tax relief on Oriel IPO


